Natasha Tirko

Natasha Tirko

Graduate Student, NYULMC



Graduate Student

Education and Training

  • B.S. in Bioengineering, Pennsylvania State University, State College, PA, 2007
  • M.S.E. in Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 2009
  • Research Associate, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 2009-2011
  • M.S. in Neuroscience, New York University, New York, NY, 2014
  • Ph.D. in Neuroscience, New York University, New York, NY, 2016

Research Interests

Synaptic strength and signal transmission in neuronal networks determines animal behavior in normal and disease conditions. I investigate changes in intrinsic cellular plasticity and network signaling as a result of neurotransmitter action, specifically neuromodulation by oxytocin, in hippocampal area CA2, a region critical for social memory.

Selected Publications

  • Groth RD, Tirko NN, Tsien RW. CaV1.2 calcium channels: just cut out to be regulated? Neuron. 2014, 82(5):939-40.
  • Wincott CM, Abera S, Vunck SA, Tirko NN, Choi Y, Titcombe RF, Antoine SO, Tukey DS, DeVito LM, Hofmann F, Hoeffer CA and Ziff EB. cGMP-dependent protein kinase typle II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits. Neurobiol Learn Mem. 2014, 114:32-9.
  • Owen SF, Tuncdemir SN, Bader PL, Tirko NN, Fishell G, Tsien RW. (2013) Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons. Nature. 500(7463):458-62.
  • Muniak MA, Connelly CJ, Tirko NN, O'Neil JN, Ryugo DK. (2013) Synaptic organization and plasticity in the auditory system of the deaf white cat. In Kral, Popper and Fay (Eds.) Deafness, Springer Handbook of Auditory Research (47th ed, pp. 83-128). Springer, New York.
  • Tirko NN, Ryugo DK. (2012) Synaptic plasticity in the medial superior olive of hearing, deaf, and cochlear implanted cats. J Comp Neurol. 520(10):2202-17.