Abdul Rasheed Alabi

Abdul Rasheed Alabi

MSTP Student, Stanford

Email

aalabi@stanford.edu; abdul.alabi@nyumc.org

Position

MSTP student, Stanford Medical School

Education and Training

  • B.S. in Biomedical Engineering, Johns Hopkins University, Baltimore, MD

Research Interests

Molecular and cellular control of non-classical (kiss-and-run) synaptic vesicle fusion and recycling. Regulated vesicle fusion and recycling is critical to the function of many vital physiological systems, particularly the complex neural circuits underlying mammalian behavior. Using novel optical readouts including molecular-level perturbations, I am interested in dissecting the cell biological control of a non-classical form of fusion called kiss-and-run (KR). KR occurs in a variety of cell-types and purportedly impacts intercellular signaling in different ways. Clarification of the mechanism and modulation of KR at a molecular level has bearing on understanding how vesicle transitions are coordinated by their cellular environment and the influence of release dynamics on neural information processing, both in health and disease.

Selected Publications

  • Alabi A.A., Tsien R.W. Perspectives on Kiss-and-Run exo-endocytosis and its role in neurotransmission. Ann Rev Physiology. 2012 (submitted).
  • Alabi A.A., Tsien R.W. Synaptic vesicle pools and dynamics. Cold Spring Harb Perspect Biol. 2012 Aug; 4(8).
  • Milescu M., Bosmans F., Lee S., Alabi A.A.,Kim J.I. and Swartz K.J. Interaction between lipids and voltage sensor paddles detected with tarantula toxins. Nat Struc Mol Biol. 2009 Oct; 16(10).
  • Alabi A.A., Bahamonde M.I., Jung H.J., Kim J.I., and Swartz K.J. Portability of paddle motif function and pharmacology in voltage sensors. Nature. 2007 Nov; 450(7168).
  • Barbieri R., Matten E.C., Alabi A.A., Brown E.N. A point process model of human heart beat intervals: new definitions of heart rate and heart rate variability. Am. J. Physiol Heart Circ Physiol. 2005 Jan; 288(1).
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